BIGL: Biochemically Intuitive Generalized Loewe Model

Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available.

Version: 1.1.0
Depends: R (≥ 2.10)
Imports: ggplot2, MASS, methods, minpack.lm, numDeriv, parallel, progress, rgl, robustbase, scales
Suggests: knitr, testthat, shiny, DT
Published: 2017-09-25
Author: Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov, Rytis Bagdziunas
Maintainer: Maxim Nazarov <maxim.nazarov at>
License: GPL-3
NeedsCompilation: no
Materials: NEWS
CRAN checks: BIGL results


Reference manual: BIGL.pdf
Vignettes: Synergy analysis
Package source: BIGL_1.1.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X El Capitan binaries: r-release: BIGL_1.1.0.tgz
OS X Mavericks binaries: r-oldrel: BIGL_1.1.0.tgz
Old sources: BIGL archive


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