Implementation of several phenotype-based family genetic risk scores
with unified input data and data preparation functions to help facilitate
the required data preparation and management. The implemented family genetic
risk scores are the extended liability threshold model conditional on family history
from Pedersen (2022) <doi:10.1016/j.ajhg.2022.01.009> and Pedersen (2023) <https://www.nature.com/articles/s41467-023-41210-z>,
Pearson-Aitken Family Genetic Risk Scores from Krebs (2024) <doi:10.1016/j.ajhg.2024.09.009>,
and family genetic risk score from Kendler (2021) <doi:10.1001/jamapsychiatry.2021.0336>.
| Version: |
1.0.1 |
| Imports: |
batchmeans, dplyr, future.apply, future, lubridate, purrr, Rcpp, rlang, stats, stringr, tibble, tmvtnorm, tidyselect, igraph, xgboost, tidyr |
| LinkingTo: |
Rcpp |
| Suggests: |
knitr, rmarkdown, testthat (≥ 3.0.0), MASS |
| Published: |
2025-08-28 |
| DOI: |
10.32614/CRAN.package.LTFGRS |
| Author: |
Emil Michael Pedersen [aut, cre],
Jette Steinbach [aut],
Lucas Rasmussen [ctb],
Morten Dybdahl Krebs [aut] |
| Maintainer: |
Emil Michael Pedersen <emp at ph.au.dk> |
| BugReports: |
https://github.com/EmilMiP/LTFGRS/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://emilmip.github.io/LTFGRS/ |
| NeedsCompilation: |
yes |
| Language: |
en-GB |
| Materials: |
README, NEWS |
| CRAN checks: |
LTFGRS results |